Bone Marrow Transplantation
Bone marrow transplant is the process to replace the destroyed or damaged bone marrow which is due to chemotherapy, infection, or disease. to healthy stem cells in bone marrow. Bone marrow is a delicate, fatty and soft tissue in the bones, which produces the blood cells. The stem cells in bone marrow are basically immature cells that produces various blood cells, as well as promote growth.
Bone marrow creates red blood cells that carry oxygen, as well as the nutrients all around the body, white blood cells that helps fight infection, and platelets also known as thrombocytes that help in forming blood clots. Bone marrow consists of HSCs or hematopoietic stem cells which are the immature stem cells forming blood. Bone marrow is required to cure various kinds of cancer, and many diseases. When radiation or chemotherapy are given in high doses to treat cancer, it causes permanent damage, for which a bone marrow transplant is needed. If you are looking for best doctors for bone marrow transplant, the you will find a huge list of bone marrow transplant doctors in India, who offer the best care.
Some of the diseases which are treated and which benefit from this transplant include of leukemia, lymphoma, severe aplastic anemia, multiple myeloma, some of the solid tumor cancers, and immune deficiency disorders. Although patients experience towards these diseases would be different, for which bone marrow transplant is not always an appropriate treatment.
It could be used to:
- Replace non-functioning, diseased bone marrow to the functioning, healthy bone marrow, which is for some conditions including sickle cell anemia, leukemia, and aplastic anemia.
- Regeneration of immune system, which will help in fighting residual or existing leukemia, or any other kinds of cancer.
- Restore the normal functioning of bone marrow which is damaged after high dosage of radiation or chemotherapy that is given to cure malignancy. Rescue is another term often used for this process. It is mainly for diseases like neuroblastoma and lymphoma.
- For genetically healthy bone marrow functioning it is replaced, to prevent any further possible harm from the genetic disease such as adrenoleukodystrophyand Hurler’s syndrome.
The benefits and possible risks should be discussed with the specialists and doctor prior the procedure of transplantation. As along with the benefits, there could be some complications, such as infections, pain, fluid overload, respiratory distress, organ damage, graft failure, etc. These all complications may depend or vary upon the preparative regimen, age, tissue match between the recipient and donor, and overall health. Although the experience of such symptoms would differ from person to person. A specialist or doctor, should discuss all these with you before the transplant, as during the process of infusion, the patient could feel chest pain, hives, fever, chills, and pain. Also after the infusion patient may require blood transfusion, extreme weakness, mouth sores, diarrhea, vomiting, nausea, temporary psychological or emotional distress. Find the best doctors for bone marrow transplant in India, who are excellent at their work, and will provide you with the best treatment.